In vivo and halotestin tablets in vitro halotestin tablets inhibits the release of mediators (histamine, leukotrienes, prostaglandins and platelet activating factor) of the cells involved in type I allergic reactions (mast cells, eosinophils, basophils and neutrophils). halotestin tablets inhibits the chemotaxis, activation and degranulation of eosinophils and stabilizes cell membranes by inhibiting phosphodiesterase and reducing cyclo-AMP. halotestin tablets also blocks H 1 – histamine receptors.
Dosing and Administration
Adults, patients over the age of 65, children older than 3 years.: For I drop into the conjunctival sac 2 times a day
in patients over the age of 65 years do not need a correction mode.
Side effect On the part of the organ of vision: Burning eyes, corneal epithelial erosion point (frequency of 1 to 2%). Reduced visual acuity with instillation of the drug, the syndrome of “dry” eye, conjunctivitis, eye pain, subconjunctival hemorrhage, photophobia, disorders of the age (incidence <1%), for example, edema and hyperemia of the eyelids, itching, etc. On the side body as a whole: headache, drowsiness, skin rash, eczema, urticaria, allergic reactions, dry mouth (incidence <1%).
Data on overdose of the drug available.
Eye drops Zaditen safe if accidentally swallowed, as in 5 ml of solution contains 1.25 mg of halotestin tablets, which is 60% of the maximum oral daily dose for children over 3 years. When administered orally at a dose of halotestin tablets and 20 mg were not marked by the development of serious symptoms.
Interaction with other drugs
The data on the interaction of Zaditen eye drops with other drugs are not available.
Zaditen, eye drops contains as a preservative benzalkonium chloride, which is able to penetrate into the material of soft contact lenses. The drug is used only after removal of contact lenses. Putting contact lenses 15 minutes after instillation.
All eye drops, which include benzalkonium chloride can discolour soft contact lenses. With the opening of the original packaging is broken sterile dropper bottle. To prevent contamination of the drug solution by instillation, patients should avoid contact tip of the dropper bottle with skin and eyes.
If necessary, the instillation of several drugs in the conjunctival cavity preparations should be applied at least 5 minutes separately with an interval.
Effects on ability to drive vehicles and use machines
In the development of blurred vision, drowsiness during treatment Zaditekom patients should give up the road management or using machinery.
Eye drops 0.25 mg / ml to 5 ml plastic bottle dropper white. 1 bottle with instruction on use in carton box.
Store at temperatures up to 25 ° C.
Keep out of reach of children.
2 years. Shelf life after opening the vial -1 months.
The drug should not be used after the expiration date.